Research Use Only - Not for human consumption. 18+ only.
BGrade BSmaller human trials, observational studies, or approved in 30+ countriesCompoundableCompoundableLegal to compound in the US; approved in other jurisdictions or has historical approvalCognitive EnhancementSubcutaneous

Selank

Also known as: Selank peptide, Tuftsin analog

A synthetic heptapeptide analog of tuftsin that modulates immune function and reduces anxiety while enhancing cognitive performance through GABA and dopamine pathways.

Beginner Basics

Plain-English guide to Selank

What it does

Selank is a synthetic peptide that researchers study for its ability to reduce anxiety and stress while supporting memory and mental clarity. It works by influencing brain chemicals related to mood and calm focus.

Typical dose

Researchers typically use 250-500 micrograms injected under the skin once or twice daily, starting at the lower dose to see how your body responds.

When to inject

Morning and/or evening at consistent times each day; many researchers prefer morning for mental clarity benefits.

Storage

Keep the dry powder sealed in a cool, dark place at room temperature. Once mixed with sterile water, store in the refrigerator and use within 2-4 weeks.

First-timer tip

Start with the lowest dose (250 mcg) and give it 2-4 weeks before increasing, so you can clearly feel what it does for you and avoid any adjustment effects.

Research Status

BGrade BSmaller human trials, observational studies, or approved in 30+ countriesCompoundableCompoundableLegal to compound in the US; approved in other jurisdictions or has historical approval

Clinical trials

For research purposes only. Not approved for human use. Not medical advice.

Research Areas

Reduces anxiety and stress responses
Enhances memory and cognitive function
Improves mood and emotional resilience
Supports immune system modulation
Increases mental clarity and focus
Promotes neuroprotection
Reduces fatigue and mental exhaustion

Side Effects

Mild headache
UncommonMild

May occur in first 1-2 weeks of use. Usually resolves with continued use or dose adjustment. Ensure adequate hydration.

Dizziness or lightheadedness
UncommonMild

Typically mild and transient. More common at higher doses. Sit or lie down if experienced; usually resolves within 30 minutes.

Insomnia or sleep disturbance
UncommonMild

May occur if injected too close to bedtime. Administer morning or early afternoon dose instead. Effects usually resolve within 1 week.

Mild nausea
RareMild

Uncommon with subcutaneous injection. May be reduced by injecting at room temperature and ensuring proper injection technique.

Local injection site reactions
UncommonMild

Mild redness, itching, or slight swelling at injection site. Prevent through proper site rotation and sterile technique. Resolves within hours.

Increased anxiety or irritability
RareModerate

Paradoxical response reported in rare cases, particularly at higher doses or in sensitive individuals. Reduce dose or discontinue and consult healthcare provider.

Mild tremor or jitteriness
RareMild

May occur at higher doses due to dopaminergic effects. Reduce dose and monitor. Usually resolves within 24-48 hours.

Allergic reaction (hypersensitivity)
RareSerious

Symptoms include rash, urticaria, angioedema, or difficulty breathing. Discontinue immediately and seek emergency medical attention if severe.

Dosing Reference

ParameterValue
Dose range250-500 mcg
Frequency, timing and route - members only

Research disclaimer

Figures drawn from published research literature and community logs. Not clinical recommendations. Consult a qualified professional. Research use only.

Reconstitution Guide

Do not use saline or bacteriostatic saline, use only bacteriostatic water for reconstitution

Do not shake the vial vigorously; gentle swirling prevents peptide degradation

Discard immediately if the solution appears cloudy, discolored, or contains visible particles

Use within 30 days of reconstitution when stored at 2-8°C

Do not freeze the reconstituted solution; freezing may denature the peptide

Use the PeptideVolt reconstitution calculator for your exact concentration

Use the PeptideVolt reconstitution calculator for your exact concentration

Molecular and Pharmacological Data

Molecular weight751.9
Half-lifeApproximately 4-6 hours (plasma); CNS effects may persist longer due to receptor binding
SequenceMembers only

Selank is a synthetic heptapeptide analog of tuftsin that crosses the blood-brain barrier and modulates neurotransmitter systems, particularly GABA and dopamine pathways. It enhances immune function through T-cell activation and cytokine modulation while simultaneously reducing anxiety and improving cognitive performance. The peptide works through multiple mechanisms including neuroprotection, anxiolysis, and immunomodulation.

Pathways and mechanism detail available to members

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Research Use Only. All content on this page is provided for informational and educational purposes related to scientific research. Selank is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.