Cognitive Enhancement / Intravenous / Intramuscular
Cerebrolysin
Also known as FPF-1070, Brain-derived peptides
Cerebrolysin is a mixture of neurotrophic peptides derived from pig brain. It mimics the effects of neurotrophic factors and shows promise for neurodegenerative diseases and traumatic brain injury.
What is Cerebrolysin used for? Research has focused on neuroprotective and neurotrophic effects; may improve cognitive function; supports stroke recovery.
Compare with other peptides studied forcognitive performance,recovery and healing
Cerebrolysin injection at a glance
Figures from the published research literature. Research use only.
- Dose range
- 5-30 mL
- Route
- Intravenous, Intramuscular
How often, when, and the dosing notes are in the dosing reference further down.
Beginner basics
Plain-English guide to Cerebrolysin
- What it does
- Cerebrolysin is a brain-derived mixture that researchers use to protect brain cells and support brain health. It's commonly studied for helping with memory, thinking clarity, and recovery from brain injuries or cognitive decline.
- Typical dose
- Researchers typically use 5-30 mL injected either into a vein (IV) or muscle (IM), usually once daily for 10-30 days, followed by a break before repeating.
- When to inject
- Morning injections are most common. Researchers typically run cycles of treatment for 10-30 days, then take a break before starting another cycle.
- Storage
- Keep the sealed vial at room temperature before opening. Once mixed with liquid, store it in the refrigerator and use within a few days.
- Beginner tip
- Start with the lowest dose in the range (around 5 mL) to see how your body responds, and always follow a cycle pattern with breaks to avoid your body becoming less responsive.
Research status
- Evidence grade B
- Smaller human trials, observational studies, or approved in 30 or more countries.
- Compoundable
- Legal to compound in the US, and approved in other jurisdictions or with a history of approval.
Approved in some countries, research compound in others
For research purposes only. Not approved for human use. Not medical advice.
Research areas
- Neuroprotective and neurotrophic effects
- May improve cognitive function
- Supports stroke recovery
- Potential for Alzheimer's and dementia
- Enhances neuroplasticity
- Improves TBI recovery
Side effects
| Effect | How often | Severity |
|---|---|---|
| Injection site pain or discomfortOccurs at IM or IV injection sites. Typically resolves within 24 hours. Reduce by allowing solution to warm to room temperature before injection and rotating injection sites. Apply ice if needed. | Common | Mild |
| Mild headacheMay occur during the first few days of treatment. Usually self-resolving. Ensure adequate hydration and rest. | Uncommon | Mild |
| Dizziness or lightheadednessMore common with IV administration. Sit or lie down if symptoms occur. Typically resolves within minutes to hours. | Uncommon | Mild |
| NauseaMay occur, especially with IV administration. Take with food if tolerated. Symptoms usually resolve within 24 hours. | Uncommon | Mild |
| Fever or chillsRare; may indicate a reaction to the porcine-derived material. Monitor temperature. If fever persists beyond 24 hours, seek medical evaluation. | Rare | Mild |
| Allergic reaction (rash, urticaria, angioedema)Cerebrolysin is derived from porcine brain tissue; individuals with porcine protein allergies are at higher risk. Symptoms may include itching, hives, facial swelling, or difficulty breathing. Seek immediate medical attention if any signs of anaphylaxis occur. Have antihistamines and epinephrine available. | Rare | Serious |
| Phlebitis or thrombophlebitis (IV administration)Inflammation of the vein at the IV site. Risk increases with prolonged IV infusions or repeated use of the same vein. Rotate IV sites and use proper aseptic technique. Symptoms include redness, warmth, swelling, or pain along the vein. Seek medical evaluation if symptoms develop. | Uncommon | Moderate |
| Muscle pain or myalgiaMay occur at or near IM injection sites. Usually resolves within 48 hours. Apply heat or take over-the-counter analgesics if needed. | Uncommon | Mild |
| Insomnia or sleep disturbanceCerebrolysin may have mild stimulant-like effects on the central nervous system. Avoid injections late in the day. Symptoms typically resolve after treatment discontinuation. | Uncommon | Mild |
| Agitation or anxietyRare; may occur in sensitive individuals. Usually mild and self-resolving. Discontinue if symptoms are bothersome and consult a healthcare provider. | Rare | Mild |
| SeizuresVery rare; reported in isolated cases, particularly in individuals with a history of seizure disorders. Cerebrolysin should be used with caution in patients with epilepsy. Seek immediate medical attention if seizure activity occurs. | Rare | Serious |
Dosing reference
Dose scale from the research
- Starting
- 5 mL
- Typical
- 10 mL
- Upper end
- 20 mL
| Parameter | Value |
|---|---|
| Dose range | 5-30 mL |
Frequency, timing and route are for members | |
Checked October 2026
Research disclaimer. Figures are drawn from published research literature and community logs. They are not clinical recommendations. Consult a qualified professional. Research use only.
Reconstitution guide
- Do not use saline or bacteriostatic saline, use only bacteriostatic water for reconstitution
- Do not shake the vial vigorously; gentle swirling prevents peptide degradation
- Discard immediately if the solution appears cloudy, discolored, or contains visible particles
- Use within 30 days of reconstitution when stored at 2-8°C
- Do not freeze the reconstituted solution; freezing may denature the peptide
- Use the PeptideVolt reconstitution calculator for your exact concentration
Storage and stability
Room temperature before opening, refrigerate after
Molecular and pharmacological data
| Half-life | Approximately 6-8 hours (estimated from clinical pharmacokinetics; exact half-life varies by individual peptide components) |
|---|
Cerebrolysin is a standardised mixture of neuropeptides and amino acids derived from porcine brain tissue that mimics the effects of endogenous neurotrophic factors, particularly nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). It crosses the blood-brain barrier and promotes neuronal survival, differentiation, and synaptic plasticity through activation of neurotrophic signalling pathways. The peptide mixture enhances cellular energy metabolism and reduces neuroinflammation, making it a candidate for treating neurodegenerative conditions and traumatic brain injury.
Keep a log of your Cerebrolysin research
Free account. No credit card required.
Recent research
All results on PubMedCerebrolysin Induces Motor Recovery Along with Plastic Changes in Motoneurons and an Increase in GAP43 Protein in the Ventral Spinal Cord Following a Kainic Acid Excitotoxic Lesion in the Rat Motor Cortex.
Martínez-Torres NI, et al. / Neurochemical research / 2024
Tau and Amyloid-β Peptides in Serum of Patients With Parkinson's Disease: Correlations With CSF Levels and Clinical Parameters.
Schirinzi T, et al. / Frontiers in neurology / 2022
Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers.
Bezdan D, et al. / iScience / 2020
Source: PubMed / NCBI. Updated daily. Articles are listed for research reference only.
Research citations
2 sources
Cerebrolysin neurotrophic effects
Peptide mixture cognitive enhancement
Related: Cognitive Enhancement
All Cognitive Enhancement peptidesCerebrolysin in blends
Browse the research library
147 peptide profiles and 59 blend profiles with mechanism summaries, dosing data and reconstitution guides.
View all peptidesStay updated on Cerebrolysin research
A weekly digest of new peptide research, stack guides and site updates.
Research use only. All content on this page is provided for informational and educational purposes related to scientific research. Cerebrolysin is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.