BPC-157
Also known as: Body Protection Compound-157, PL 14736, Bepecin
BPC-157 is a pentadecapeptide derived from a protective protein found in human gastric juice. It has shown remarkable healing properties for various tissues including tendons, ligaments, muscles, and the gastrointestinal tract.
Research Status
Research compound with extensive animal studies
For research purposes only. Not approved for human use. Not medical advice.
Research Areas
Side Effects
Typically resolves within 30-60 minutes. Rotate injection sites to minimize.
Usually occurs in the first few days of use and subsides as the body adjusts.
May occur shortly after injection. Sit down and hydrate if experienced.
Extremely rare. Discontinue use immediately and seek medical attention if rash, swelling, or difficulty breathing occurs.
Dosing Reference
| Parameter | Value |
|---|---|
| Dose range | 250-500 mcg |
| Frequency | 1-2x daily |
| Timing | Morning and/or evening, can be taken with food |
| Route | Subcutaneous, Intramuscular, Oral |
Can be injected near injury site for localized healing or taken systemically. Also effective orally for gut issues.
Research disclaimer
Figures drawn from published research literature and community logs. Not clinical recommendations. Consult a qualified professional. Research use only.
Reconstitution Guide
Do not use saline or bacteriostatic saline — use only bacteriostatic water for reconstitution
Do not shake the vial vigorously; gentle swirling prevents peptide degradation
Discard immediately if the solution appears cloudy, discolored, or contains visible particles
Use within 30 days of reconstitution when stored at 2–8°C
Do not freeze the reconstituted solution; freezing may denature the peptide
Use the PeptideVolt reconstitution calculator for your exact concentration
Molecular and Pharmacological Data
| Molecular weight | 1419.53 Da |
| Half-life | Approximately 4 hours (subcutaneous) |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
BPC-157 is a 15-amino acid peptide derived from human gastric juice that exerts cytoprotective and regenerative effects across multiple tissue types. It acts through several biological pathways to accelerate wound healing, reduce inflammation, and promote angiogenesis (new blood vessel growth).
VEGF Pathway (Angiogenesis)
Upregulates vascular endothelial growth factor (VEGF) expression, promoting the formation of new blood vessels to injured areas and improving blood supply for tissue repair.
FAK-Paxillin Pathway (Tendon/Ligament Repair)
Activates the focal adhesion kinase (FAK) and paxillin signaling pathway, which is critical for tendon and ligament cell migration, adhesion, and proliferation during healing.
Nitric Oxide (NO) System
Modulates the nitric oxide system to provide anti-inflammatory effects, protect the gastrointestinal mucosa, and support vascular function during tissue recovery.
Growth Hormone Receptor Expression
Upregulates growth hormone receptor expression in injured tissue, enhancing the local response to circulating growth hormone and amplifying the healing cascade.
- Only known compound that simultaneously upregulates growth hormone receptor expression in injured tissue
- Effective across multiple tissue types: tendons, ligaments, muscles, gut lining, skin, and bone
- Cytoprotective — protects cells from damage caused by NSAIDs, alcohol, and other toxins
- Does not interact with the HPA axis, making it distinct from corticosteroids
- Derived from a naturally occurring protective protein in human gastric juice (BPC)
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View all peptidesResearch Use Only. All content on this page is provided for informational and educational purposes related to scientific research. BPC-157 is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.