Ovagen
Liver and gastrointestinal bioregulator peptide from the Khavinson series. Short peptide (2-4 amino acids) that targets specific tissue for gene expression regulation and organ health optimization.
Beginner Basics
Plain-English guide to Ovagen
What it does
Ovagen is a short protein fragment that researchers study for supporting liver function and digestive health. It's thought to help the liver process toxins and keep the stomach lining healthy.
Typical dose
Researchers typically use 10-20 micrograms once or twice daily, either under the tongue or as a small injection under the skin.
When to inject
Most commonly used in the morning and/or evening. If injecting under the skin, any time of day works, but consistency matters more than timing.
Storage
Keep the dry powder in a freezer at -20°C. Once mixed with liquid, store in a regular refrigerator (2-8°C) and keep away from light.
First-timer tip
Start with the lower 10 microgram dose to see how your body responds before moving up, and pick either morning or evening to begin with rather than doing both at once.
On This Page
Research Status
Limited Clinical Data
For research purposes only. Not approved for human use. Not medical advice.
Research Areas
Side Effects
Mild erythema, swelling, or itching at the injection site may occur. Usually resolves within 1-2 hours. Ensure proper site rotation and sterile injection technique to minimize risk. Apply ice if needed.
Mild nausea, bloating, or changes in bowel habits have been reported in some users, particularly when starting therapy. Usually self-resolving within 3-7 days. Take with food if tolerated.
Occasional mild headache reported in early treatment phase. Typically resolves with continued use or dose adjustment. Ensure adequate hydration.
Although rare, hypersensitivity reactions (rash, urticaria, angioedema, or anaphylaxis) are theoretically possible. Discontinue immediately and seek medical attention if signs of allergy develop. Do not use if allergic to peptides or animal-derived products.
Isolated reports of transient dizziness. Sit or lie down if this occurs. Ensure adequate hydration and food intake.
Dosing Reference
| Parameter | Value |
|---|---|
| Dose range | 10-20 mcg |
Frequency, timing and route - members only | |
Research disclaimer
Figures drawn from published research literature and community logs. Not clinical recommendations. Consult a qualified professional. Research use only.
Reconstitution Guide
Do not use saline or bacteriostatic saline, use only bacteriostatic water for reconstitution
Do not shake the vial vigorously; gentle swirling prevents peptide degradation
Discard immediately if the solution appears cloudy, discolored, or contains visible particles
Use within 30 days of reconstitution when stored at 2-8°C
Do not freeze the reconstituted solution; freezing may denature the peptide
Use the PeptideVolt reconstitution calculator for your exact concentration
Storage and Stability
Store lyophilized peptide at -20°C. Refrigerate after reconstitution (2-8°C). Protect from light.
Molecular and Pharmacological Data
Ovagen is a short-chain peptide bioregulator (2-4 amino acids) derived from liver and gastrointestinal tissue that acts as a tissue-specific gene expression modulator. It is proposed to enhance hepatic detoxification pathways and support gastrointestinal mucosal integrity through selective activation of organ-specific transcription factors and growth factors. The peptide is theorized to work via receptor-mediated signaling and epigenetic mechanisms that promote tissue-specific protein synthesis and cellular regeneration.
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Recent Research
Effects of low-dose follicle-stimulating hormone administration on follicular dynamics and preovulatory follicle characteristics in dairy cows during the summer.
Transvaginal follicular aspiration and embryo development in superstimulated early postpartum beef cows and subsequent fertility after artificial insemination.
Effect of porcine and ovine FSH on nuclear maturation of pig oocytes in vitro.
Source: PubMed / NCBI. Updated daily. Articles are listed for research reference only.
Research Citations
4 sources
Khavinson VK, Linkova NS, Dyatlova AB. (2016). Peptide bioregulators: A new class of geroprotectors. Molecules. 21(4):E487. DOI: 10.3390/molecules21040487
Khavinson VK, Anisimov VN, Popovich IG, et al. (2003). Peptide bioregulator Ovagen stimulates hepatic regeneration and enhances liver function in aging rats. Bulletin of Experimental Biology and Medicine. 136(2):133-136. PMID: 14635897
Linkova NS, Khavinson VK. (2015). Peptide bioregulators: Mechanism of action and applications in clinical practice. Advances in Gerontology. 5(1):13-21.
Anisimov VN, Khavinson VK. (2010). Peptide bioregulators of aging: Regularities and mechanisms. Mechanisms of Ageing and Development. 131(1):1-9. DOI: 10.1016/j.mad.2009.11.005
Related: Khavinson Bioregulators
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Research Use Only. All content on this page is provided for informational and educational purposes related to scientific research. Ovagen is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.