AOD-9604
Also known as: Advanced Obesity Drug, Fragment 176-191
AOD-9604 is a modified fragment of growth hormone that specifically targets fat metabolism without affecting blood sugar. It promotes lipolysis and has no effects on insulin or glucose.
Beginner Basics
Plain-English guide to AOD-9604
What it does
This is a small piece of a natural growth hormone that tells your body to break down and burn stored fat. Researchers use it because it targets fat specifically without affecting blood sugar or insulin levels.
Typical dose
250-500 micrograms injected under the skin once daily.
When to inject
First thing in the morning before eating, on an empty stomach.
Storage
Keep the dry powder at room temperature until mixed. After mixing with water, store in the refrigerator and use within the timeframe on your kit instructions.
First-timer tip
Inject on an empty stomach in the morning and wait at least 30 minutes before eating to get the best effect, since food can interfere with how it works.
On This Page
Research Status
Research compound
For research purposes only. Not approved for human use. Not medical advice.
Research Areas
Side Effects
Mild redness, swelling, or bruising at the injection site. Typically resolves within 1-2 hours. Minimise by allowing the solution to reach room temperature, using proper injection technique, and rotating injection sites. Apply ice if swelling persists.
Mild to moderate headache reported in some users, typically occurring within 1-2 hours of injection. Usually self-resolving within a few hours. Ensure adequate hydration and consider taking the injection with a light meal if headaches persist.
Transient flushing or sensation of warmth in the face or upper body, typically lasting 15-30 minutes. No intervention required; resolves spontaneously.
Mild dizziness reported in some users, particularly if injected while standing. Sit or lie down for 5-10 minutes after injection if this occurs. Ensure adequate hydration.
Mild nausea reported in some users, typically transient. Taking the injection with a small amount of food or ginger may help. If persistent, consult a healthcare provider.
Repeated injections in the same site can cause localised fat loss or indentation of the skin due to the lipolytic effects of the peptide. Prevent by strictly rotating injection sites with each dose, maintaining at least 1 inch between injection points, and cycling through at least 4 different anatomical sites.
Although AOD-9604 does not directly affect insulin secretion, increased fat oxidation may theoretically lower blood glucose in susceptible individuals, particularly those with diabetes or on glucose-lowering medications. Monitor blood glucose if diabetic. Seek medical attention if symptoms of hypoglycaemia (tremor, sweating, confusion) occur.
Severe allergic reactions (anaphylaxis) are extremely rare but possible. Symptoms include difficulty breathing, swelling of the face or throat, severe rash, or rapid heartbeat. Seek emergency medical attention immediately if these symptoms occur. Discontinue use and inform your healthcare provider of any known allergies to growth hormone or peptides.
Prolonged use of growth hormone fragments may rarely cause carpal tunnel syndrome due to fluid retention or tissue changes. Symptoms include numbness, tingling, or weakness in the hand or wrist. If symptoms develop, discontinue use and consult a healthcare provider.
Dosing Reference
| Parameter | Value |
|---|---|
| Dose range | 250-500 mcg |
Frequency, timing and route - members only | |
Research disclaimer
Figures drawn from published research literature and community logs. Not clinical recommendations. Consult a qualified professional. Research use only.
Reconstitution Guide
Do not use saline or bacteriostatic saline, use only bacteriostatic water for reconstitution
Do not shake the vial vigorously; gentle swirling prevents peptide degradation
Discard immediately if the solution appears cloudy, discolored, or contains visible particles
Use within 30 days of reconstitution when stored at 2-8°C
Do not freeze the reconstituted solution; freezing may denature the peptide
Use the PeptideVolt reconstitution calculator for your exact concentration
Molecular and Pharmacological Data
| Molecular weight | 2149 |
| Half-life | Approximately 30 minutes (subcutaneous) |
| Sequence | Members only |
AOD-9604 is a synthetic C-terminal fragment of human growth hormone (amino acids 176-191) that activates the GH receptor on adipose tissue, specifically triggering lipolysis (fat breakdown) without stimulating insulin secretion or affecting blood glucose levels. Unlike full-length growth hormone, this fragment selectively targets fat metabolism through the GH secretagogue pathway, making it useful for metabolic research and weight management studies.
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View all peptidesResearch Use Only. All content on this page is provided for informational and educational purposes related to scientific research. AOD-9604 is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.