5-Amino-1MQ
Also known as: 1MQ, 5-Amino-1-methylquinolinium
NNMT (nicotinamide N-methyltransferase) inhibitor that promotes fat loss by increasing NAD+ levels and enhancing cellular energy metabolism.
Beginner Basics
Plain-English guide to 5-Amino-1MQ
What it does
This compound works by blocking an enzyme in your cells that normally slows down energy production, allowing your cells to burn more fat and produce more energy. Researchers study it because it may help increase metabolism and support weight loss.
Typical dose
Researchers commonly use 50-100 mg taken once or twice daily by mouth, usually starting at the lower dose to see how your body responds.
When to inject
Take it in the morning or split the dose between morning and evening, ideally with food to help your body absorb it.
Storage
Keep the powder at room temperature (15-25°C) in a dry place away from light and moisture in its original container. Do not refrigerate unless the manufacturer says to.
First-timer tip
Start with 50 mg once per day for at least a week to see how your body tolerates it before increasing to twice daily, since research data in humans is still limited.
On This Page
Research Status
Early Research
For research purposes only. Not approved for human use. Not medical advice.
Research Areas
Side Effects
Often occurs when taken on an empty stomach. Mitigate by taking with food. Usually resolves within 1-2 weeks as tolerance develops.
May occur during initial dosing. Ensure adequate hydration and consider dose reduction if persistent.
Possible due to increased metabolic rate and NAD+ activation. Avoid dosing in late afternoon or evening; take morning dose only.
May occur due to elevated metabolic rate. Monitor heart rate; discontinue and seek medical evaluation if severe or persistent.
May indicate dehydration or blood pressure changes. Ensure adequate fluid intake and monitor blood pressure.
Expected effect related to metabolic enhancement. Ensure adequate caloric and nutrient intake to support health.
Reported in preclinical studies at high doses. Monitor liver function if using for extended periods; discontinue if enzymes become significantly elevated.
Dosing Reference
| Parameter | Value |
|---|---|
| Dose range | 50-100 mg |
Frequency, timing and route - members only | |
Research disclaimer
Figures drawn from published research literature and community logs. Not clinical recommendations. Consult a qualified professional. Research use only.
Reconstitution Guide
Do not use saline or bacteriostatic saline, use only bacteriostatic water for reconstitution
Do not shake the vial vigorously; gentle swirling prevents peptide degradation
Discard immediately if the solution appears cloudy, discolored, or contains visible particles
Use within 30 days of reconstitution when stored at 2-8°C
Do not freeze the reconstituted solution; freezing may denature the peptide
Use the PeptideVolt reconstitution calculator for your exact concentration
Molecular and Pharmacological Data
5-Amino-1MQ inhibits NNMT, an enzyme that consumes NAD+ cofactors. By blocking NNMT activity, the compound increases intracellular NAD+ availability, which activates sirtuins and enhances mitochondrial function. This leads to increased energy expenditure, improved fat oxidation, and metabolic rate elevation.
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Recent Research
Axial couplings and strong decay widths of heavy hadrons.
Heavy baryon masses in the 1/mQ and 1/Nc expansions.
Phenomenology of the 1/mQ expansion in inclusive B and D meson decays.
Source: PubMed / NCBI. Updated daily. Articles are listed for research reference only.
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View all peptidesResearch Use Only. All content on this page is provided for informational and educational purposes related to scientific research. 5-Amino-1MQ is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.