Alexamorelin
A ghrelin mimetic that stimulates GH release. Research compound with appetite-stimulating effects.
Beginner Basics
Plain-English guide to Alexamorelin
What it does
Alexamorelin tricks your body into releasing more growth hormone, which researchers study for building muscle and increasing appetite. It mimics a natural hunger signal in your body.
Typical dose
Researchers typically use 100-300 micrograms (a tiny amount) injected under the skin, once to three times per day. Most start at the lowest dose and increase gradually.
When to inject
Best used before meals or before bed. Timing isn't critical, but before eating takes advantage of its appetite effects.
Storage
Keep the dry powder in a freezer at -20°C (about -4°F). Once you mix it with liquid, store it in a regular refrigerator at 2-8°C (35-46°F) and keep it away from direct light.
First-timer tip
Start with the 100 microgram dose for at least a few days to see how your body responds before increasing, since this is a research compound and effects vary between people.
On This Page
Research Status
Early Research
For research purposes only. Not approved for human use. Not medical advice.
Research Areas
Side Effects
Expected pharmacological effect. Occurs within 30-60 minutes of injection. May be beneficial for those seeking to increase caloric intake but problematic for those on caloric restriction.
Mild erythema, swelling, or discomfort at injection site. Usually resolves within hours. Minimize by rotating injection sites, using room-temperature solution, and ensuring proper injection technique.
Reported in some users, typically mild and transient. May be related to GH secretion or individual sensitivity.
Transient vasodilation reported in some users. Usually resolves within 15-30 minutes of injection.
Reported rarely. Sit or lie down if experienced. Ensure adequate hydration.
Uncommon but reported by some users. Usually mild and transient. May be minimized by injecting on a full stomach.
Localized fat loss or thickening at repeated injection sites. Preventable through systematic site rotation. Rotate sites with each injection and avoid injecting into the same location more than once per week.
GH secretagogues may transiently elevate cortisol. Clinically significant elevation is rare with alexamorelin. Monitor if using chronically.
Minor prolactin elevation reported in some studies. Typically not clinically significant with short-term use.
Anaphylaxis or severe allergic reaction is rare but possible. Seek immediate medical attention if experiencing difficulty breathing, severe swelling, or chest pain. Discontinue use immediately.
Dosing Reference
| Parameter | Value |
|---|---|
| Dose range | 100-300 mcg |
Frequency, timing and route - members only | |
Research disclaimer
Figures drawn from published research literature and community logs. Not clinical recommendations. Consult a qualified professional. Research use only.
Reconstitution Guide
Do not use saline or bacteriostatic saline, use only bacteriostatic water for reconstitution
Do not shake the vial vigorously; gentle swirling prevents peptide degradation
Discard immediately if the solution appears cloudy, discolored, or contains visible particles
Use within 30 days of reconstitution when stored at 2-8°C
Do not freeze the reconstituted solution; freezing may denature the peptide
Use the PeptideVolt reconstitution calculator for your exact concentration
Molecular and Pharmacological Data
Alexamorelin is a synthetic ghrelin receptor agonist that binds to the growth hormone secretagogue receptor 1a (GHS-R1a) on anterior pituitary somatotroph cells. This binding stimulates the release of growth hormone in a dose-dependent manner. Additionally, alexamorelin activates ghrelin signaling pathways in the hypothalamus and gastrointestinal tract, leading to increased appetite and food intake, similar to endogenous ghrelin.
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View all peptidesResearch Use Only. All content on this page is provided for informational and educational purposes related to scientific research. Alexamorelin is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.