What is the typical dose of Adipotide?

Typical research doses are 0.5-1 mg, administered 1x daily. These are research figures only — not clinical recommendations.

What are the known side effects of Adipotide?

Side effects reported in research include: Acute kidney injury (common, serious); Hepatotoxicity (common, serious); Injection site reactions (uncommon, mild); Fatigue (uncommon, mild); Nausea (uncommon, mild); Vascular complications (rare, serious); Coagulopathy (uncommon, serious). Always consult a qualified professional before use.

How is Adipotide administered?

Adipotide is typically administered via Subcutaneous.

Can Adipotide be injected?

In the research literature, Adipotide is described with subcutaneous administration. This is research information only, not medical advice.

What is the evidence quality for Adipotide?

Adipotide carries an evidence grade of D. Grade D — theoretical or very preliminary evidence only.

Specialized Peptides / Subcutaneous

Adipotide

Q: What is Adipotide used for in research?

Research on Adipotide has focused on: Reduces adipose tissue mass; Targets visceral fat deposits; Induces selective fat cell apoptosis; May improve metabolic markers.

Also known as FTPP, Prohibitin-TP01

An experimental peptidomimetic that targets and destroys fat tissue blood supply through a targeted proapoptotic peptide. Causes fat cell death by cutting off blood supply to adipose tissue.

What is Adipotide used for? Research has focused on reduces adipose tissue mass; targets visceral fat deposits; induces selective fat cell apoptosis.

Compare with other peptides studied forfat loss,recovery and healing

Evidence grade DResearch only

Adipotide injection at a glance

Figures from the published research literature. Research use only.

Dose range: 0.5-1 mg
Route: Subcutaneous

How often, when, and the dosing notes are in the dosing reference further down.

Work out your units in the free calculator

Beginner basics

Plain-English guide to Adipotide

What it does: This experimental peptide works by cutting off the blood supply to fat cells, which causes them to die and shrink. Researchers study it because it targets fat tissue directly, especially deep belly fat, and may help improve how the body processes energy.
Typical dose: Research typically uses 0.5-1 mg once daily, injected under the skin. Important note: this is based on animal studies only-human dosing is completely unknown.
When to inject: No specific time requirement. Inject once daily at whatever time is convenient for you.
Storage: Keep the dry powder in the freezer at -20°C. Once you mix it with liquid, store it in the refrigerator between 2-8°C and keep it away from direct light.
Beginner tip: This peptide is still experimental with documented safety concerns and has never been tested in humans-understand the significant risks before using, and consider starting at the lower end of the dose range if you proceed.

Research status

Evidence grade D: Theoretical or in-vitro only, with no meaningful independent human evidence.
Research only: No regulatory approval in any major jurisdiction. Research use only.

Early Research

For research purposes only. Not approved for human use. Not medical advice.

Research areas

Reduces adipose tissue mass
Targets visceral fat deposits
Induces selective fat cell apoptosis
May improve metabolic markers

Side effects

Effect	How often	Severity
Acute kidney injuryDocumented in preclinical studies at therapeutic doses. Manifests as elevated serum creatinine and blood urea nitrogen. Mechanism may involve vascular disruption in renal tissue or direct endothelial toxicity. Requires immediate medical evaluation and discontinuation.	Common	Serious
HepatotoxicityElevated liver enzymes (ALT, AST) observed in animal studies. Potential mechanism involves off-target vascular effects in hepatic tissue. Requires liver function monitoring and medical evaluation.	Common	Serious
Injection site reactionsLocal erythema, induration, or mild pain at injection site. Typically resolves within 24-48 hours. Rotate injection sites to minimize recurrence.	Uncommon	Mild
FatigueMay occur due to rapid metabolic changes or systemic effects. Usually mild and self-resolving.	Uncommon	Mild
NauseaReported in some preclinical studies. Typically mild and transient.	Uncommon	Mild
Vascular complicationsPotential for off-target vascular effects in tissues other than adipose tissue. Risk of thrombosis, hemorrhage, or ischemic injury to vital organs. Requires immediate medical attention.	Rare	Serious
CoagulopathyVascular disruption may trigger abnormal clotting. Requires hematologic monitoring and medical evaluation.	Uncommon	Serious

Dosing reference

Dose scale from the research

Starting: 0.5 mg
Upper end: 1 mg

Adipotide dosing reference
Parameter	Value
Dose range	0.5-1 mg
Frequency, timing and route are for members Sign up free Log in

Checked October 2026

Research disclaimer. Figures are drawn from published research literature and community logs. They are not clinical recommendations. Consult a qualified professional. Research use only.

Reconstitution guide

Do not use saline or bacteriostatic saline, use only bacteriostatic water for reconstitution
Do not shake the vial vigorously; gentle swirling prevents peptide degradation
Discard immediately if the solution appears cloudy, discolored, or contains visible particles
Use within 30 days of reconstitution when stored at 2-8°C
Do not freeze the reconstituted solution; freezing may denature the peptide
Use the PeptideVolt reconstitution calculator for your exact concentration

Worked example

With 5 mg in the vial, the water you add changes the draw. Mixed with 1 mL that is 5,000 mcg per mL, so on a U-100 syringe 0.5 mg is 10 units and 1 mg is 20 units. Mixed with 2 mL it is 2,500 mcg per mL, so 0.5 mg is 20 units and 1 mg is 40 units.

Work out your exact dose in the free peptide calculator

Storage and stability

Store lyophilized peptide at -20°C. Refrigerate after reconstitution (2-8°C). Protect from light.

Molecular and pharmacological data

Adipotide is a peptidomimetic that targets the vasculature of adipose tissue through a proapoptotic mechanism. The peptide binds to integrin receptors on endothelial cells within fat tissue blood vessels, triggering apoptosis (programmed cell death) of these vascular cells. This vascular disruption cuts off blood supply to adipocytes, leading to selective fat cell death and reduction of adipose tissue mass.

Pathways and mechanism detail are for members

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Recent research

All results on PubMed

Mixed-Chirality Prohibitin Peptide: D-(RLARLAR)2 Enhances Stability and In Vivo Effects on Obesity.
Chan LY, et al. / Journal of the American Chemical Society / 2025

Source: PubMed / NCBI. Updated daily. Articles are listed for research reference only.

Research citations

3 sources

Kolonin MG, et al. (2004). Reversal of obesity by targeted ablation of adipose tissue. Nat Med. 10(6):625-32. PMID: 15133506
Zaragosi LE, et al. (2010). Activin A plays a critical role in proliferation and differentiation of human adipose progenitors. J Cell Physiol. 224(1):178-86. PMID: 20232316
Rupnick MA, et al. (2002). Adipose tissue mass can be regulated through the vasculature. Proc Natl Acad Sci USA. 99(16):10730-5. PMID: 12149466

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Research use only. All content on this page is provided for informational and educational purposes related to scientific research. Adipotide is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.