YK11
A myostatin inhibitor with SARM-like properties that promotes muscle growth by increasing follistatin levels. Uniquely acts as both a selective androgen receptor modulator and myostatin inhibitor.
Research Status
Early Research
For research purposes only. Not approved for human use. Not medical advice.
Research Areas
Side Effects
YK11 is metabolized hepatically. Limited human data, but oral SARMs have shown liver enzyme elevation in some users. Monitor liver function tests (AST, ALT, bilirubin) if using. Discontinue if jaundice or severe abdominal pain develops.
As an AR modulator, YK11 may suppress endogenous testosterone production through negative feedback. Post-cycle therapy (PCT) with SERMs may be considered after 8-12 week cycles, though evidence is limited.
May occur with oral administration, especially on an empty stomach. Take with food to minimize. Usually resolves within days of continued use.
Reported anecdotally in some users. Typically mild and self-resolving. Ensure adequate hydration.
Possible due to androgen receptor activation. Maintain good skin hygiene and consider dermatologist consultation if severe.
Possible in genetically predisposed individuals due to AR activation in hair follicles. Risk may be lower than traditional steroids but is not zero. Discontinue if significant hair loss occurs.
Anecdotal reports of mood alterations. Monitor mental health and discontinue if significant mood disturbance occurs.
YK11 has not been studied in humans. Long-term safety, efficacy, and potential organ toxicity are unknown. Use carries inherent research risk.
Dosing Reference
| Parameter | Value |
|---|---|
| Dose range | 5-10 mg |
| Frequency | 1x daily |
| Timing | Morning, with food |
| Route | Subcutaneous |
Oral administration. Research compound with limited human safety data. Often cycled 8-12 weeks with 4-week breaks. Not approved for human use.
Research disclaimer
Figures drawn from published research literature and community logs. Not clinical recommendations. Consult a qualified professional. Research use only.
Reconstitution Guide
Do not use saline or bacteriostatic saline — use only bacteriostatic water for reconstitution
Do not shake the vial vigorously; gentle swirling prevents peptide degradation
Discard immediately if the solution appears cloudy, discolored, or contains visible particles
Use within 30 days of reconstitution when stored at 2–8°C
Do not freeze the reconstituted solution; freezing may denature the peptide
Use the PeptideVolt reconstitution calculator for your exact concentration
Molecular and Pharmacological Data
YK11 functions as a selective androgen receptor (AR) modulator with dual activity as a myostatin inhibitor. It promotes muscle growth by increasing follistatin expression, which suppresses myostatin — a negative regulator of muscle mass. Unlike traditional anabolic steroids, YK11 exhibits tissue-selective effects and may promote myogenic differentiation with reduced virilization potential, though human safety data remains limited.
Androgen Receptor Signaling
YK11 binds to and activates androgen receptors in muscle tissue, promoting anabolic gene expression and protein synthesis without full systemic androgenic effects
Myostatin Inhibition via Follistatin
YK11 increases follistatin production, which binds to and neutralizes myostatin, a negative regulator of muscle growth. This allows increased muscle protein synthesis and hypertrophy
Myogenic Differentiation
YK11 promotes the conversion of myoblasts into mature muscle fibers through enhanced differentiation pathways, contributing to increased muscle mass
- YK11 is a non-steroidal selective androgen receptor modulator (SARM) with myostatin-inhibiting properties
- Increases follistatin expression, which suppresses myostatin and promotes muscle growth
- Promotes myogenic differentiation in cell culture without requiring classical androgen receptor-dependent virilization
- Research is limited to in vitro and animal studies; human pharmacokinetics and long-term safety are not well-established
- Not approved for human use by any regulatory agency
Track your YK11 research
Free account. No credit card required.
Browse the Research Library
40+ peptide profiles with mechanism summaries, dosing data, and reconstitution guides.
View all peptidesResearch Use Only. All content on this page is provided for informational and educational purposes related to scientific research. YK11 is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.