What is Cardiogen used for in research?

Research on Cardiogen has focused on: Supports cardiac muscle function and contractility; Promotes heart tissue regeneration and repair; Enhances myocardial energy metabolism; Supports healthy blood pressure regulation; May improve exercise tolerance in cardiac patients; Supports vascular endothelial function.

What is the typical dose of Cardiogen?

Typical research doses are 10-20 mcg, administered 1x daily. Commonly timed: Morning, subcutaneous or sublingual. These are research figures only — not clinical recommendations.

What are the known side effects of Cardiogen?

Side effects reported in research include: Local injection site reactions (uncommon, mild); Mild headache (uncommon, mild); Dizziness or lightheadedness (rare, mild); Allergic reaction (rare, serious); Lipodystrophy (uncommon, moderate). Always consult a qualified professional before use.

How is Cardiogen administered?

Cardiogen is typically administered via Subcutaneous.

Can Cardiogen be injected?

In the research literature, Cardiogen is described with subcutaneous administration. This is research information only, not medical advice.

What is the evidence quality for Cardiogen?

Cardiogen carries an evidence grade of C. Grade C — supported by animal studies or in-vitro research.

Khavinson Bioregulators / Subcutaneous

Cardiogen

Heart muscle bioregulator peptide from the Khavinson series. Short peptide (2-4 amino acids) that targets specific tissue for gene expression regulation and organ health optimization.

What is Cardiogen used for? Research has focused on supports cardiac muscle function and contractility; promotes heart tissue regeneration and repair; enhances myocardial energy metabolism.

Compare with other peptides studied forrecovery and healing,muscle growth

Evidence grade CResearch only

Cardiogen injection at a glance

Figures from the published research literature. Research use only.

Dose range: 10-20 mcg
Route: Subcutaneous

How often, when, and the dosing notes are in the dosing reference further down.

Work out your units in the free calculator

Beginner basics

Plain-English guide to Cardiogen

What it does: This is a short chain of amino acids designed to support heart muscle function and help the heart work more efficiently. Researchers study it for its potential to help heart tissue repair itself and improve how well the heart contracts.
Typical dose: Researchers typically use 10-20 micrograms once per day, starting at the lower end (10 mcg) to check how your body responds.
When to inject: Inject in the morning, either just under the skin or under the tongue. Timing within the day isn't critical, but morning is the standard practice.
Storage: Keep the dry powder in a freezer at -20°C. Once you mix it with liquid, store it in a regular refrigerator (2-8°C) and keep it away from light.
Beginner tip: Start with the 10 mcg dose and give yourself at least a week to see how you tolerate it before considering any adjustments, since this peptide hasn't been as widely studied in Western countries as some others.

Research status

Evidence grade C: Mostly animal or in-vitro studies, with limited human data.
Research only: No regulatory approval in any major jurisdiction. Research use only.

Limited Clinical Data

For research purposes only. Not approved for human use. Not medical advice.

Research areas

Supports cardiac muscle function and contractility
Promotes heart tissue regeneration and repair
Enhances myocardial energy metabolism
Supports healthy blood pressure regulation
May improve exercise tolerance in cardiac patients
Supports vascular endothelial function

Side effects

Effect	How often	Severity
Local injection site reactionsMild redness, swelling, or itching at the injection site may occur. Usually resolves within 1-2 hours. Rotate injection sites to minimize recurrence. Apply ice if needed.	Uncommon	Mild
Mild headacheOccasional headache reported in early use. Typically resolves within 24-48 hours. Ensure adequate hydration and consider taking the injection in the evening if morning dosing causes discomfort.	Uncommon	Mild
Dizziness or lightheadednessRare reports of transient dizziness. Sit or lie down if this occurs. Ensure you are well-hydrated and have eaten a light meal before injection.	Rare	Mild
Allergic reactionRare but serious risk with any peptide. Signs include rash, difficulty breathing, swelling of face or throat, or severe itching. Seek immediate medical attention if these symptoms occur. Discontinue use and inform your healthcare provider.	Rare	Serious
LipodystrophyRepeated injections at the same site may cause localized fat loss or thickening. Prevent by rotating injection sites systematically. Do not inject into the same site more than once per week.	Uncommon	Moderate

Dosing reference

Dose scale from the research

Starting: 10 mcg
Typical: 15 mcg
Upper end: 20 mcg

Cardiogen dosing reference
Parameter	Value
Dose range	10-20 mcg
Frequency, timing and route are for members Sign up free Log in

Checked October 2026

Research disclaimer. Figures are drawn from published research literature and community logs. They are not clinical recommendations. Consult a qualified professional. Research use only.

Reconstitution guide

Do not use saline or bacteriostatic saline, use only bacteriostatic water for reconstitution
Do not shake the vial vigorously; gentle swirling prevents peptide degradation
Discard immediately if the solution appears cloudy, discolored, or contains visible particles
Use within 30 days of reconstitution when stored at 2-8°C
Do not freeze the reconstituted solution; freezing may denature the peptide
Use the PeptideVolt reconstitution calculator for your exact concentration

Worked example

With 5 mg in the vial, the water you add changes the draw. Mixed with 1 mL that is 5,000 mcg per mL, so on a U-100 syringe 10 mcg is 0.2 units and 20 mcg is 0.4 units. Mixed with 2 mL it is 2,500 mcg per mL, so 10 mcg is 0.4 units and 20 mcg is 0.8 units.

Work out your exact dose in the free peptide calculator

Storage and stability

Store lyophilized peptide at -20°C. Refrigerate after reconstitution (2-8°C). Protect from light.

Molecular and pharmacological data

Cardiogen is a short-chain peptide bioregulator that is hypothesized to regulate gene expression specifically in cardiac muscle tissue through tissue-selective signaling pathways. The peptide is proposed to enhance myocardial energy metabolism, support cardiomyocyte survival and regeneration, and promote healthy vascular endothelial function. The exact molecular mechanism remains incompletely characterized in Western literature, though Russian research suggests it may modulate growth factors and metabolic pathways critical to cardiac homeostasis.

Pathways and mechanism detail are for members

Keep a log of your Cardiogen research

Free account. No credit card required.

Start free Goal finder Interaction checker

Recent research

All results on PubMed

Source: PubMed / NCBI. Updated daily. Articles are listed for research reference only.

Research citations

4 sources

Khavinson VKh, Linkova NS, Dyatlova AB. (2016). Peptide bioregulators: A new class of drugs for gerontological research and clinical practice. Advances in Gerontology. 6(1):41-49.
PubMed PMID: 27749917. Study on Khavinson peptide bioregulators and their tissue-specific effects on gene expression in cardiac and vascular tissues.
Korkushko OV, Shatilo VB, Dudnyk VM, Khavinson VKh. (2011). Peptide bioregulator effects on age-related changes in cardiovascular system. Bulletin of Experimental Biology and Medicine. 151(4):488-491.
Anisimov VN, Khavinson VKh. (2010). Peptide bioregulation of aging: Results and prospects. Biogerontology. 11(2):139-149.

All Khavinson Bioregulators peptides

Browse the research library

147 peptide profiles and 59 blend profiles with mechanism summaries, dosing data and reconstitution guides.

View all peptides

Stay updated on Cardiogen research

A weekly digest of new peptide research, stack guides and site updates.

Research use only. All content on this page is provided for informational and educational purposes related to scientific research. Cardiogen is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.