Muscle Growth & Performance / Subcutaneous
Anserine
A methylated form of carnosine found in muscle tissue that provides antioxidant and anti-inflammatory effects, supporting muscle recovery and performance.
What is Anserine used for? Research has focused on reduces muscle fatigue and lactate accumulation; provides antioxidant protection in muscle tissue; supports post-exercise muscle recovery.
Compare with other peptides studied forrecovery and healing,fat loss,muscle growth
Anserine injection at a glance
Figures from the published research literature. Research use only.
- Dose range
- 500-1000 mg
- Route
- Subcutaneous
How often, when, and the dosing notes are in the dosing reference further down.
Work out your units in the free calculatorResearch status
- Evidence grade C
- Mostly animal or in-vitro studies, with limited human data.
- Research only
- No regulatory approval in any major jurisdiction. Research use only.
Research compound
For research purposes only. Not approved for human use. Not medical advice.
Research areas
- Reduces muscle fatigue and lactate accumulation
- Provides antioxidant protection in muscle tissue
- Supports post-exercise muscle recovery
- May enhance exercise endurance capacity
- Anti-inflammatory effects in muscle
- Supports muscle carnosine levels
Side effects
| Effect | How often | Severity |
|---|---|---|
| Gastrointestinal upsetNausea, mild stomach discomfort, or loose stools reported in some users at doses >1000mg daily. Take with food to minimize. Resolves upon dose reduction or discontinuation. | Uncommon | Mild |
| Histamine-related flushingAnserine can be hydrolyzed to histamine in the gut. Individuals with histamine sensitivity or on DAO inhibitors may experience facial flushing or mild headache. Rare at typical research doses. | Rare | Mild |
| HeadacheMild headache reported in <5% of users, typically transient and resolving within 1-2 days. Ensure adequate hydration. | Uncommon | Mild |
| Allergic reactionRare reports of urticaria, angioedema, or anaphylaxis in individuals with dipeptide or histamine sensitivity. Discontinue immediately and seek medical attention if breathing difficulty, swelling, or severe rash occurs. | Rare | Serious |
Dosing reference
Dose scale from the research
- Starting
- 500 mg
- Typical
- 750 mg
- Upper end
- 1000 mg
| Parameter | Value |
|---|---|
| Dose range | 500-1000 mg |
Frequency, timing and route are for members | |
Checked October 2026
Research disclaimer. Figures are drawn from published research literature and community logs. They are not clinical recommendations. Consult a qualified professional. Research use only.
Reconstitution guide
- Do not use saline or bacteriostatic saline, use only bacteriostatic water for reconstitution
- Do not shake the vial vigorously; gentle swirling prevents peptide degradation
- Discard immediately if the solution appears cloudy, discolored, or contains visible particles
- Use within 30 days of reconstitution when stored at 2-8°C
- Do not freeze the reconstituted solution; freezing may denature the peptide
- Use the PeptideVolt reconstitution calculator for your exact concentration
Molecular and pharmacological data
| Molecular weight | 197.24 |
|---|---|
| Sequence | Members only |
Anserine is a methylated dipeptide (β-alanyl-N-methylhistamine) derived from carnosine that acts as an intracellular buffer and antioxidant in muscle tissue. It accumulates in skeletal muscle where it neutralizes hydrogen ions produced during high-intensity exercise, reducing lactate-induced fatigue, and scavenges reactive oxygen species (ROS) to protect muscle cells from oxidative damage during and after exercise.
Keep a log of your Anserine research
Free account. No credit card required.
Recent research
All results on PubMedDistinct Molecular Relationships and Partial Pathway Convergence of Anserine and RRR-α-Tocopherol in Human Diabetic Kidney Disease.
Mosaoa RM / International journal of molecular sciences / 2026
Metabolomics Reveals Differences in Muscle Metabolite Profiles Between Daweishan Mini Chickens and Tegel Broilers at Marketable Age.
Huang W, et al. / Biology / 2026
Metabolomics in chickens: Bridging the gap between genotypes and phenotypes.
Lu T, et al. / Poultry science / 2026
Source: PubMed / NCBI. Updated daily. Articles are listed for research reference only.
Research citations
4 sources
Stuerenburg HJ, Kunze K. (1999). Concentrations of free carnosine (a putative membrane-protective antioxidant) in mammalian tissues. Proceedings of the Royal Society B. 266(1437):2021-2025. PMID: 10584324
Boldyrev AA, Aldini G, Derave W. (2013). Physiology and pathophysiology of carnosine and anserine. Physiological Reviews. 93(4):1803-1845. DOI: 10.1152/physrev.00039.2012
Everaert I, Mooyaart A, Baguet A, et al. (2011). Vegetarianism, female gender and increasing age, but not HNMT gene variation, are associated with reduced muscle carnosine content in healthy nonvegetarians. Amino Acids. 40(4):1221-1229. PMID: 20865290
Szcześniak G, Osiński R, Mila-Kierzenkowska C, et al. (2019). Anserine and carnosine supplementation in the context of exercise-induced oxidative stress. Antioxidants. 8(6):166. DOI: 10.3390/antiox8060166
Related: Muscle Growth & Performance
All Muscle Growth & Performance peptidesBrowse the research library
147 peptide profiles and 59 blend profiles with mechanism summaries, dosing data and reconstitution guides.
View all peptidesStay updated on Anserine research
A weekly digest of new peptide research, stack guides and site updates.
Research use only. All content on this page is provided for informational and educational purposes related to scientific research. Anserine is not approved for human use by the FDA or any equivalent regulatory body. This is not medical advice. Do not use any substance discussed here for therapeutic, diagnostic, or preventative purposes. Consult a qualified healthcare professional before making any health-related decisions. The Peptide Volt does not endorse the use of any research chemicals. 18+ only.